Thomas von Lueder Molecular Mechanisms of Cardiac Hypertrophy and Heart Failure

Thomas von Lueder Molecular Mechanisms of Cardiac Hypertrophy and Heart Failure

скачать

Heart failure (HF) is a major cause of death worldwide. Remodeling of the heart plays an important role in the development of HF. von Lueder et. Important aspects of cardiac function are controlled by G protein-coupled receptors (GPCR). GPCR signaling is shut off by a small group of enzymes called GRKs. Dr. Importantly, GRK3ct mice were prevented from HF when subjected to sustained severe cardiac stress for up... Pulmonary congestion increased the number of inflammatory cells as well as ET-1 production. Activiation of the vasoconstrictor endothelin-1 (ET-1) in HF has multiple adverse effects on the cardiovascular system. identified the lungs as a major source of increased ET-1 levels in a HF model. al. In genetically-engineered mice (GRK3ct), GRK3 inhibition enhanced cardiac function, presumably through continuous ?-adrenergic signaling. When HF animals were treated with a macrophage blocker in follow-up experiments, ET-1 levels were reduced and, importantly, cardiac function improved.

Джорджия Бирс Слишком близко, чтобы коснуться

Жизнь усложняется, когда любовь оказывается не совсем то, что ты ожидаешь. Гретхен - одна из немногих женщин-руководителей добившаяся успеха на корпоративной арене,...

Delfin: Horverstehen: Teil 1 (аудиокурс на 4 CD)

Horverstehen, Teil 1, Lektion 1-10. Horverstehentexte, Sprechubungen und Diktate. Die 4 CDs enthalten alle Hortexte zu Delfin,...

Железнова Л. Теория бух. учета Уч.-метод. комплекс

2 комментария на “Thomas von Lueder Molecular Mechanisms of Cardiac Hypertrophy and Heart Failure

  1. Тахир так и головной с приездом в руке, весть на неё: - Ну, вибрировать или.

Добавить комментарий

Ваш e-mail не будет опубликован. Обязательные поля помечены *